The typical age of menopause in Brazil is between 50 and 51 years. Nevertheless, resulting from genetic components, pre-existing illnesses, surgical procedures, or most frequently for unknown causes, some ladies cease menstruating utterly earlier than the age of 40. It is a situation known as untimely ovarian failure (POI).
In medical phrases, menopause happens on the date of a girl’s final menstrual interval. It’s a pure occasion that marks the top of a human’s reproductive life.
When the ovaries cease working, the physique is with out the functioning of estrogen, the primary feminine hormone, and an individual is extra prone to develop bone and cardiovascular issues, in addition to lose fertility.
He says Gynecologist Christina Laguna, Chairman of the Nationwide Committee for Gynecological Endocrinology in Vibrasgo.
What’s the distinction between untimely menopause and untimely ovarian failure?
In response to the Vibrasgo gynecologist, early menopause is the one that happens between the ages of 40 and 50. If the bleeding stops sooner than that, it is a signal of IOP.
Some docs name untimely ovarian failure untimely menopause, however we don’t like that comparability. Menopause has a connotation related to a level of regular growing old. He says that it isn’t physiological for the ovaries to cease working earlier than the age of forty.
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Latest research present that IOP impacts 3.7% of girls, says the physician, who can also be a professor within the Division of Obstetrics and Gynecology at Unicamp’s School of Medical Sciences.
Prior to now, there was discuss of a 1% unfold. Nevertheless, because the publicity round the issue will increase, extra persons are in search of care and receiving a prognosis. As well as, most cancers therapies have improved. Many younger sufferers who’ve undergone chemotherapy and radiotherapy have gone on to have IOP,” she explains.
What are the causes of early menopause and untimely ovarian failure?
The explanations are the identical in each situations. Mainly, something that damages the ovaries or prevents the physique from producing estrogen can result in menopause. In response to Christina Laguna, the primary triggers are:
– heredity: if an individual has a member of the family who stops menstruating early, the chance of him having the identical drawback will increase;
Autoimmune illnesses: People with these circumstances may have autoimmune illnesses towards the ovaries.
– Iatrogenic components: operations to take away the uterus and ovaries, in addition to radiotherapy and chemotherapy, may cause IOP.
Publicity to bodily and infectious brokers: It’s identified that viral infections, extreme smoking and pesticides, for instance, can act as endocrine disruptors. Nevertheless, a cause-and-effect relationship can’t be established.
Nevertheless, in 60% of instances, we don’t know why the ovaries cease working. Persons are born with much less follicular reserve or have prematurely spent their follicles,” notes the gynecologist.
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How is early menopause and untimely ovarian failure handled?
The therapy in both case is just like menopause: hormone substitute remedy. Nevertheless, in IOP, the doses administered are increased and tailored to the traits of the younger lady.
Therapy goals to revive enough ranges of hormones, notably estrogen. This hormone performs an essential function within the improvement of the reproductive organs throughout puberty, equivalent to the event of the breasts and uterus. As well as, it’s related to elevated bone mass, which helps forestall osteoporosis.
In response to Professor Unicamp, research present that estrogen deficiency can also be related to temper swings, melancholy, anxiousness, decreased cognitive capability, sleep issues and a higher tendency to dementia.
“Estrogen is the primary hormone within the feminine organism, not just for replica, however for all these capabilities that it performs. The sooner the lack of ovarian operate, the higher the chance to a girl’s well being,” says the gynecologist.
Progesterone is changed in ladies who’ve a uterus to guard towards endometrial most cancers. In these with a historical past of endometriosis, it prevents the illness from reappearing.
Therapy additionally contains steering about wholesome habits, equivalent to quitting smoking, consuming a balanced weight loss program, avoiding being chubby, and being bodily energetic. Psychological follow-up is important for an individual to take care of the emotional challenges related to a prognosis.
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